A database of hormones and their receptors
Peptide Hormone

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HMRbase accession number11533
Swiss-prot Accession numberP41160 (Sequence in FASTA format)
DescriptionLeptin;Alternative Name: Obesity factor; Precursor
Source organismMus musculus (Mouse)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus.
Subcellular locationSecreted (Probable)
Developmental StageN/A
Similarity Belongs to the leptin family.
Tissue SpecificityN/A
Post translational modification N/A
Function May function as part of a signaling pathway that acts to regulate the size of the body fat depot. An increase in the level of LEP may act directly or indirectly on the CNS to inhibit food intake and/or regulate energy expenditure as part of a homeostatic mechanism to maintain constancy of the adipose mass.
Protein Length167 Amino acids
Molecular weight18709
References1  PubMed abstract 7984236
Domain NameLeptin  
Hormone NameLeptin
Mature Hormone Sequence
Position of mature hormone in Pre-Hormone protein
ReceptorP48356   Detail in HMRbase   
Q9CQ74   Detail in HMRbase   
O89013   Detail in HMRbase   
A2AV64   Detail in HMRbase   
A2AV69   Detail in HMRbase   
Q3UNU8   Detail in HMRbase   
Q3US58   Detail in HMRbase   
Q545G9   Detail in HMRbase   
Gene ID16846      
PDB IDN/A
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