A database of hormones and their receptors
Peptide Hormone

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HMRbase accession number11377
Swiss-prot Accession numberP06850 (Sequence in FASTA format)
DescriptionCorticoliberin precursor (Corticotropin-releasing factor) (CRF)(Corticotropin-releasing hormone).
Source organismHomo sapiens (Human)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionThis hormone from hypothalamus regulates the release of corticotropin from pituitary gland
Protein Length196 Amino acids
Molecular weight21422
References1  PubMed abstract 6605851
2  PubMed abstract 2783917
3   Kalnine N., Chen X., Rolfs A., Halleck A., Hines L., Eisenstein S.,Koundinya M., Raphael J., Moreira D., Kelley T., LaBaer J., Lin Y.,Phelan M., Farmer A.; "Cloning of human full-length CDSs in BD Creator(TM) system donorvector."; Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
4  PubMed abstract 15489334
5  PubMed abstract 3262120
6  PubMed abstract 8386360
Domain NameCRF  
Hormone NameCorticoliberin
Mature Hormone SequenceSEEPPISLDLTFHLLREVLEMARAEQLAQQAHSNRKLMEII
Position of mature hormone in Pre-Hormone protein41 Residues from position (154-194)
ReceptorP34998   Detail in HMRbase   
Q13324    Detail in HMRbase   
Gene ID1392      
PDB IDN/A
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