A database of hormones and their receptors
Peptide Hormone

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HMRbase accession number10378
Swiss-prot Accession numberQ9YGK4 (Sequence in FASTA format)
DescriptionCorticotropin-lipotropin 1 precursor (Corticotropin-lipotropin I)(Pro-opiomelanocortin I) (POMC I) [Contains: Corticotropin(Adrenocorticotropic hormone) (ACTH); Melanotropin alpha (Alpha-MSH);Corticotropin-like intermediary peptide (CLIP); Lipotropin beta (Beta-LPH); Lipotropin gamma (Gamma-LPH); Melanotropin beta (Beta-MSH);Beta-endorphin; Met-enkephalin].
Source organismCyprinus carpio (Common carp)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;Cyprinidae; Cyprinus.
Subcellular locationN/A
Developmental StageN/A
Similarity Belongs to the POMC family.
Tissue SpecificityN/A
Post translational modification Specific enzymatic cleavages at paired basic residues yield the different active peptides.
FunctionN/A
Protein Length222 Amino acids
Molecular weight25417
References1  PubMed abstract 9806347
2  PubMed abstract 9806347
Domain NameNPP  ACTH_domain  Op_neuropeptide  
Hormone NameMet-enkephalin
Mature Hormone SequenceYGGFM
Position of mature hormone in Pre-Hormone protein5 Residues from position (190-194)
ReceptorQ683Z6   Detail in HMRbase   
Q683Z7   Detail in HMRbase   
Q6EWJ2    Detail in HMRbase   
Gene IDN/A
PDB IDN/A
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