A database of hormones and their receptors


Pfam Domain(s) Search Results (E-value <= 1e-3)


Search Parameters
KeywordPkinase_Tyr
DatabaseReceptor
No of entries found9


Receptor database Search result 1
HMRbase accession number20028
Swiss-prot accession numberQ28616
DomainsPkinase    Pkinase_Tyr        
Function On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for anti-Muellerian hormone.


Receptor database Search result 2
HMRbase accession number20979
Swiss-prot accession numberP06213
DomainsPkinase_Tyr    Recep_L_domain    Furin-like    Pkinase        
Function This receptor binds insulin and has a tyrosine-protein kinase activity. Isoform Short has a higher affinity for insulin. Mediates the metabolic functions of insulin. Binding to insulin stimulates association of the receptor with downstream mediators including IRS1 and phosphatidylinositol 3'-kinase (PI3K). Can activate PI3K either directly by binding to the p85 regulatory subunit, or indirectly via IRS1.


Receptor database Search result 3
HMRbase accession number20983
Swiss-prot accession numberP15127
DomainsPkinase_Tyr    Recep_L_domain    Furin-like    Pkinase        
Function This receptor binds insulin and has a tyrosine-protein kinase activity.


Receptor database Search result 4
HMRbase accession number20984
Swiss-prot accession numberP15208
DomainsPkinase_Tyr    Recep_L_domain    Furin-like    Pkinase        
Function This receptor binds insulin and has a tyrosine-protein kinase activity.


Receptor database Search result 5
HMRbase accession number21074
Swiss-prot accession numberQ16671
DomainsPkinase    Pkinase_Tyr        
Function On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for anti-Muellerian hormone.


Receptor database Search result 6
HMRbase accession number21110
Swiss-prot accession numberQ62893
DomainsPkinase    Pkinase_Tyr        
Function On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for anti-Muellerian hormone.


Receptor database Search result 7
HMRbase accession number21148
Swiss-prot accession numberQ8K592
DomainsPkinase    Pkinase_Tyr        
Function On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for anti-Muellerian hormone.


Receptor database Search result 8
HMRbase accession number21196
Swiss-prot accession numberQ9PVZ4
DomainsPkinase_Tyr    Recep_L_domain    Furin-like    Pkinase        
Function This receptor binds insulin and has a tyrosine-protein kinase activity. May be required for forelimb regeneration.


Receptor database Search result 9
HMRbase accession number22067
Swiss-prot accession numberQ64895
DomainsHormone_recep    Pkinase_Tyr    zf-C4        
Function N/A