| General Property |
| Molceule ID (DB) | EGIN0003947 |
| Inhibitor Class | Anilino-quinazoline |
| Molecule Name in Refrence Article | 10 compound |
| IUPAC Name | N-(4-chloro-2-fluorophenyl)-6-methoxy-7-{[(2E)-4-(pyrrolidin-1-yl)but-2-en-1-yl]oxy}quinazolin-4-amine |
| Formula | C23H24ClFN4O2 |
| Mass | 442.914 |
| Exact Mass | 442.1571819 |
| Composition | C (62.37%), H (5.46%), Cl (8%), F (4.29%), N (12.65%), O (7.22%) |
| Atom Count | 55 |
| PI | 11.34 |
| Smiles | c12c(Nc3c(cc(cc3)Cl)F)ncnc1cc(c(c2)OC)OC/C=C/CN1CCCC1 |
| InChI | 1S/C23H24ClFN4O2/c1-30-21-13-17-20(14-22(21)31-11-5-4-10-29-8-2-3-9-29)26-15-27-23(17)28-19-7-6-16(2
4)12-18(19)25/h4-7,12-15H,2-3,8-11H2,1H3,(H,26,27,28)/b5-4+ |
| InChIKey | BMEKKWWFQMYXPU-SNAWJCMRSA-N |
| 2D Structure |  | Structure Backbone |  |
|
| View Structure in Jmol | Click to view 3 d structure Download Mol File |
| Drug Like Property | Druglikeliness |
| Symmetry & Geometry | Symmetry And Geometrical Information |
| Activity & Binding | Activity against isoform and covalant binding information |
| Topological Properties | Descriptors |
| Reference | 11881999 |
| Compounds from Reference | Other compounds from reference |
| Find Similar Compounds | |
| Reported activity against other enzymes | FGFR | KDR | Flt1 | ALL |
| Pub Chem Link |
5329038
|
| Drug Bank Link | - |
| ChemSpider Link | 4486200 |
| ChEMBL Link | CHEMBL28148 |
