General Property |
Molceule ID (DB) | EGIN0003778 |
Inhibitor Class | Pyrido-pyrimidine |
Molecule Name in Refrence Article | 53 compound |
IUPAC Name | 6-(2,6-dichlorophenyl)-2-[(4-methoxy-3-methylphenyl)amino]-8-methyl-7H,8H-pyrido[2,3-d]pyrimidin-7-one |
Formula | C22H18Cl2N4O2 |
Mass | 441.31 |
Exact Mass | 440.0806813 |
Composition | C (59.88%), H (4.11%), Cl (16.07%), N (12.7%), O (7.25%) |
Atom Count | 48 |
PI | 7.67 |
Smiles | n1(c2nc(ncc2cc(c1=O)c1c(Cl)cccc1Cl)Nc1cc(c(cc1)OC)C)C |
InChI | 1S/C22H18Cl2N4O2/c1-12-9-14(7-8-18(12)30-3)26-22-25-11-13-10-15(21(29)28(2)20(13)27-22)19-16(23)5-4-
6-17(19)24/h4-11H,1-3H3,(H,25,26,27) |
InChIKey | PBDZUUYDHCFPJM-UHFFFAOYSA-N |
2D Structure | ![](./image/EGIN0003778.png) | Structure Backbone | ![](./frame/f_EGIN0003778.png) |
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View Structure in Jmol | Click to view 3 d structure Download Mol File |
Drug Like Property | Druglikeliness |
Symmetry & Geometry | Symmetry And Geometrical Information |
Activity & Binding | Activity against isoform and covalant binding information |
Topological Properties | Descriptors |
Reference | 9703473 |
Compounds from Reference | Other compounds from reference |
Find Similar Compounds | |
Reported activity against other enzymes | PDGFr | FGFr | c-Src | ALL |
Pub Chem Link |
5327899
|
Drug Bank Link | - |
ChemSpider Link | 4485069 |
ChEMBL Link | CHEMBL113023 |