Epidermal Growth Factor Receptor Inhibitor Database


General Property
Molceule ID (DB)EGIN0003742
Inhibitor ClassIndolinone
Molecule Name in Refrence Article60 compound
IUPAC Name(3E)-3-[(5-methylfuran-2-yl)methylidene]-2,3-dihydro-1H-indol-2-one
FormulaC14H11NO2
Mass225.2426
Exact Mass225.0789786
Composition C (74.65%), H (4.92%), N (6.22%), O (14.21%)
Atom Count28
PI4.65
SmilesC1(=Cc2oc(cc2)C)/C(=O)Nc2c1cccc2
InChI1S/C14H11NO2/c1-9-6-7-10(17-9)8-12-11-4-2-3-5-13(11)15-14(12)16/h2-8H,1H3,(H,15,16)/b12-8+
InChIKeyDWJWWZSAYOTJGO-XYOKQWHBSA-N
2D Structure
Structure Backbone
View Structure in JmolClick to view 3 d structure                            Download Mol File
Drug Like PropertyDruglikeliness
Symmetry & GeometrySymmetry And Geometrical Information
Activity & Binding Activity against isoform and covalant binding information
Topological PropertiesDescriptors
Reference9651163
Compounds from ReferenceOther compounds from reference
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Reported activity against other enzymesIGF1R | PDGFR | FLK-1 | ALL
Pub Chem Link 2358462
Drug Bank Link -
ChemSpider Link 1761769
ChEMBL Link CHEMBL89697
 
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