| General Property |
| Molceule ID (DB) | EGIN0003458 |
| Inhibitor Class | Pyrazolo-pyrimidine |
| Molecule Name in Refrence Article | 4c compound |
| IUPAC Name | 2-methylpropyl N-(4-{7-amino-3-[4-(4-methylpiperazin-1-yl)phenyl]pyrazolo[1,5-a]pyrimidin-6-yl}phenyl)carbamate |
| Formula | C28H33N7O2 |
| Mass | 499.6073 |
| Exact Mass | 499.2695733 |
| Composition | C (67.31%), H (6.66%), N (19.62%), O (6.4%) |
| Atom Count | 70 |
| PI | 10.41 |
| Smiles | c1(ccc(cc1)N1CCN(CC1)C)c1c2ncc(c3ccc(cc3)NC(=O)OCC(C)C)c(n2nc1)N |
| InChI | 1S/C28H33N7O2/c1-19(2)18-37-28(36)32-22-8-4-20(5-9-22)24-16-30-27-25(17-31-35(27)26(24)29)21-6-10-23
(11-7-21)34-14-12-33(3)13-15-34/h4-11,16-17,19H,12-15,18,29H2,1-3H3,(H,32,36) |
| InChIKey | DAZCBQNFGSWSQG-UHFFFAOYSA-N |
| 2D Structure |  | Structure Backbone |  |
|
| View Structure in Jmol | Click to view 3 d structure Download Mol File |
| Drug Like Property | Druglikeliness |
| Symmetry & Geometry | Symmetry And Geometrical Information |
| Activity & Binding | Activity against isoform and covalant binding information |
| Topological Properties | Descriptors |
| Reference | 20483608 |
| Compounds from Reference | Other compounds from reference |
| Find Similar Compounds | |
| Reported activity against other enzymes | Alk | Cdk2A | c-Met | FGFR3K | IGF1R | Ins1R | Jak1 | Jak2 | Jak3 | PDK1 | PKA | PKB alpha | Syk | Zap70 | TIE2 | Lck | c-AblT315 | c-Abl | KDR | Ret | c-Src | PDGFRa | c-Kit | Hck | ALL |
| Pub Chem Link |
24762205
|
| Drug Bank Link | - |
| ChemSpider Link | 24662080 |
| ChEMBL Link | CHEMBL1085511 |
