| General Property |
| Molceule ID (DB) | EGIN0003147 |
| Inhibitor Class | Imidazo-pyrazine |
| Molecule Name in Refrence Article | 2 compound |
| IUPAC Name | 1-(3-{8-[(pyridin-4-ylmethyl)amino]imidazo[1,2-a]pyrazin-6-yl}phenyl)-3-[3-(trifluoromethyl)phenyl]urea |
| Formula | C26H20F3N7O |
| Mass | 503.4785 |
| Exact Mass | 503.1681429 |
| Composition | C (62.02%), H (4%), F (11.32%), N (19.47%), O (3.18%) |
| Atom Count | 57 |
| PI | 8.82 |
| Smiles | c1(cccc(c1)NC(=O)Nc1cccc(c1)c1cn2c(c(n1)NCc1ccncc1)ncc2)C(F)(F)F |
| InChI | 1S/C26H20F3N7O/c27-26(28,29)19-4-2-6-21(14-19)34-25(37)33-20-5-1-3-18(13-20)22-16-36-12-11-31-24(36)
23(35-22)32-15-17-7-9-30-10-8-17/h1-14,16H,15H2,(H,32,35)(H2,33,34,37) |
| InChIKey | NWEIPABWNQPRCZ-UHFFFAOYSA-N |
| 2D Structure |  | Structure Backbone |  |
|
| View Structure in Jmol | Click to view 3 d structure Download Mol File |
| Drug Like Property | Druglikeliness |
| Symmetry & Geometry | Symmetry And Geometrical Information |
| Activity & Binding | Activity against isoform and covalant binding information |
| Topological Properties | Descriptors |
| Reference | 19879134 |
| Compounds from Reference | Other compounds from reference |
| Find Similar Compounds | |
| Reported activity against other enzymes | Abl1 | Flt3 | VEGFR2 | EphA2 | Akt | Blk | CDK5 | EGFR | FGFR4 | Fyn | GSK-3b | IGFR | IRK | LCK | PKA | PKC alpha | PKC beta 2 | PKC theta | SRC | Syk | Zap70 | Lyn | EphB4 | Tie2 | VEGFR3 | VEGFR1 | PDGFR beta | Btk | ALL |
| Pub Chem Link |
11755812
|
| Drug Bank Link | - |
| ChemSpider Link | 9930515 |
| ChEMBL Link | CHEMBL1081198 |
