Epidermal Growth Factor Receptor Inhibitor Database


General Property
Molceule ID (DB)EGIN0002337
Inhibitor ClassPyrimidine
Molecule Name in Refrence Article7 compound
IUPAC Name2-imino-5-[(1Z,3S)-2-(2-methoxyphenyl)-3-methylpent-1-en-1-yl]-2H,3H-furo[2,3-d]pyrimidin-4-amine
FormulaC19H22N4O2
Mass338.4036
Exact Mass338.174276
Composition C (67.44%), H (6.55%), N (16.56%), O (9.46%)
Atom Count47
PI12.76
SmilesCC[C@H](C)/C(=C/c1coc2c1c(N)[nH]c(=N)n2)/c1ccccc1OC
InChI1S/C19H22N4O2/c1-4-11(2)14(13-7-5-6-8-15(13)24-3)9-12-10-25-18-16(12)17(20)22-19(21)23-18/h5-11H,4H2
,1-3H3,(H4,20,21,22,23)/b14-9-/t11-/m0/s1
InChIKeyGGNUJBNONVTLHE-HOXUKUGESA-N
2D Structure
Structure Backbone
View Structure in JmolClick to view 3 d structure                            Download Mol File
Drug Like PropertyDruglikeliness
Symmetry & GeometrySymmetry And Geometrical Information
Activity & Binding Activity against isoform and covalant binding information
Topological PropertiesDescriptors
Reference19748785
Compounds from ReferenceOther compounds from reference
Find Similar Compounds
                                   

Reported activity against other enzymesVEGFR2 | PDGFR beta | DHFR human | ALL
Pub Chem Link -
Drug Bank Link -
ChemSpider Link 26353724 25058903
ChEMBL Link CHEMBL603849
 
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