Epidermal Growth Factor Receptor Inhibitor Database


General Property
Molceule ID (DB)EGIN0002307
Inhibitor ClassThiazolo-pyrimidine
Molecule Name in Refrence Article6k compound
IUPAC Name4-({7-[(3-chloro-4-fluorophenyl)amino]-[1,3]thiazolo[4,5-d]pyrimidin-2-yl}amino)-N,N-bis(2-methoxyethyl)benzene-1-sulfonamide
FormulaC23H24ClFN6O4S2
Mass567.056
Exact Mass566.0973006
Composition C (48.72%), H (4.27%), Cl (6.25%), F (3.35%), N (14.82%), O (11.29%), S (11.31%)
Atom Count61
PI7.26
Smilesn1c(sc2c1ncnc2Nc1cc(c(cc1)F)Cl)Nc1ccc(cc1)S(=O)(=O)N(CCOC)CCOC
InChI1S/C23H24ClFN6O4S2/c1-34-11-9-31(10-12-35-2)37(32,33)17-6-3-15(4-7-17)29-23-30-22-20(36-23)21(26-14-
27-22)28-16-5-8-19(25)18(24)13-16/h3-8,13-14H,9-12H2,1-2H3,(H2,26,27,28,29,30)
InChIKeyAMIDDZHJRZVVOK-UHFFFAOYSA-N
2D Structure
Structure Backbone
View Structure in JmolClick to view 3 d structure                            Download Mol File
Drug Like PropertyDruglikeliness
Symmetry & GeometrySymmetry And Geometrical Information
Activity & Binding Activity against isoform and covalant binding information
Topological PropertiesDescriptors
Reference19286381
Compounds from ReferenceOther compounds from reference
Find Similar Compounds
                                   

Reported activity against other enzymesNo activity data against other kinases present in database
Pub Chem Link 16037089
Drug Bank Link -
ChemSpider Link 13165682
ChEMBL Link CHEMBL470010
 
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