Epidermal Growth Factor Receptor Inhibitor Database


General Property
Molceule ID (DB)EGIN0001913
Inhibitor ClassNaphthyridine
Molecule Name in Refrence Article28 compound
IUPAC Name4-(cyclopropylamino)-6-[(pyridin-3-ylmethyl)amino]-1,7-naphthyridine-3-carbonitrile
FormulaC18H16N6
Mass316.3598
Exact Mass316.1436445
Composition C (68.34%), H (5.1%), N (26.56%)
Atom Count40
PI12.32
Smilesc1ncc(cc1)CNc1ncc2c(c1)c(c(cn2)C#N)NC1CC1
InChI1S/C18H16N6/c19-7-13-10-21-16-11-23-17(22-9-12-2-1-5-20-8-12)6-15(16)18(13)24-14-3-4-14/h1-2,5-6,8,1
0-11,14H,3-4,9H2,(H,21,24)(H,22,23)
InChIKeyOTWLNXLUULJDHT-UHFFFAOYSA-N
2D Structure
Structure Backbone
View Structure in JmolClick to view 3 d structure                            Download Mol File
Drug Like PropertyDruglikeliness
Symmetry & GeometrySymmetry And Geometrical Information
Activity & Binding Activity against isoform and covalant binding information
Topological PropertiesDescriptors
Reference17664070
Compounds from ReferenceOther compounds from reference
Find Similar Compounds
                                   

Reported activity against other enzymesTpl2 |
Pub Chem Link 44435408
Drug Bank Link -
ChemSpider Link 23298410
ChEMBL Link CHEMBL446633
 
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