Epidermal Growth Factor Receptor Inhibitor Database


General Property
Molceule ID (DB)EGIN0001910
Inhibitor ClassNaphthyridine
Molecule Name in Refrence Article25 compound
IUPAC Name4-(phenylamino)-6-[(pyridin-3-ylmethyl)amino]-1,7-naphthyridine-3-carbonitrile
FormulaC21H16N6
Mass352.3919
Exact Mass352.1436445
Composition C (71.58%), H (4.58%), N (23.85%)
Atom Count43
PI11
Smilesc1ncc(cc1)CNc1ncc2c(c1)c(c(cn2)C#N)Nc1ccccc1
InChI1S/C21H16N6/c22-10-16-13-24-19-14-26-20(25-12-15-5-4-8-23-11-15)9-18(19)21(16)27-17-6-2-1-3-7-17/h1-
9,11,13-14H,12H2,(H,24,27)(H,25,26)
InChIKeyJUUYPIPTLXPQLH-UHFFFAOYSA-N
2D Structure
Structure Backbone
View Structure in JmolClick to view 3 d structure                            Download Mol File
Drug Like PropertyDruglikeliness
Symmetry & GeometrySymmetry And Geometrical Information
Activity & Binding Activity against isoform and covalant binding information
Topological PropertiesDescriptors
Reference17664070
Compounds from ReferenceOther compounds from reference
Find Similar Compounds
                                   

Reported activity against other enzymesTpl2 |
Pub Chem Link 44435405
Drug Bank Link -
ChemSpider Link 23298407
ChEMBL Link CHEMBL238322
 
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