Epidermal Growth Factor Receptor Inhibitor Database


General Property
Molceule ID (DB)EGIN0001859
Inhibitor ClassMethylidene-hydantoin
Molecule Name in Refrence Article2h compound
IUPAC Name(5E)-5-[(3,4-dimethyl-1H-pyrrol-2-yl)methylidene]-1-(2-phenylethyl)imidazolidine-2,4-dione
FormulaC18H19N3O2
Mass309.3624
Exact Mass309.1477269
Composition C (69.88%), H (6.19%), N (13.58%), O (10.34%)
Atom Count42
PINo isoelectric point.
SmilesC1(=Cc2[nH]cc(c2C)C)/N(C(=O)NC1=O)CCc1ccccc1
InChI1S/C18H19N3O2/c1-12-11-19-15(13(12)2)10-16-17(22)20-18(23)21(16)9-8-14-6-4-3-5-7-14/h3-7,10-11,19H,8
-9H2,1-2H3,(H,20,22,23)/b16-10+
InChIKeyCKMFCLYAKWVRSZ-MHWRWJLKSA-N
2D Structure
Structure Backbone
View Structure in JmolClick to view 3 d structure                            Download Mol File
Drug Like PropertyDruglikeliness
Symmetry & GeometrySymmetry And Geometrical Information
Activity & Binding Activity against isoform and covalant binding information
Topological PropertiesDescriptors
Reference16713265
Compounds from ReferenceOther compounds from reference
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Reported activity against other enzymesNo activity data against other kinases present in database
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