Epidermal Growth Factor Receptor Inhibitor Database


General Property
Molceule ID (DB)EGIN0001763
Inhibitor ClassPyrrolo-pyrimidine
Molecule Name in Refrence Article7b (R-Enantiomer)
IUPAC Name(2R)-2-[(5R)-4-amino-5-phenyl-5H,6H,7H-pyrrolo[2,3-d]pyrimidin-7-yl]-2-phenylethan-1-ol
FormulaC20H20N4O
Mass332.399
Exact Mass332.1637113
Composition C (72.27%), H (6.06%), N (16.86%), O (4.81%)
Atom Count45
PI10.88
Smilesc1(ncnc2c1[C@H](CN2[C@H](c1ccccc1)CO)c1ccccc1)N
InChI1S/C20H20N4O/c21-19-18-16(14-7-3-1-4-8-14)11-24(20(18)23-13-22-19)17(12-25)15-9-5-2-6-10-15/h1-10,13
,16-17,25H,11-12H2,(H2,21,22,23)/t16-,17+/m1/s1
InChIKeyBCPCKGLIPLIYKJ-SJORKVTESA-N
2D Structure
Structure Backbone
View Structure in JmolClick to view 3 d structure                            Download Mol File
Drug Like PropertyDruglikeliness
Symmetry & GeometrySymmetry And Geometrical Information
Activity & Binding Activity against isoform and covalant binding information
Topological PropertiesDescriptors
Reference11277535
Compounds from ReferenceOther compounds from reference
Find Similar Compounds
                                   

Reported activity against other enzymesc-Src | ALL
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