| General Property |
| Molceule ID (DB) | EGIN0001759 |
| Inhibitor Class | Pyrido-pyrimidine |
| Molecule Name in Refrence Article | PD-0180970 |
| IUPAC Name | 6-(2,6-dichlorophenyl)-2-[(4-fluoro-3-methylphenyl)amino]-8-methyl-7H,8H-pyrido[2,3-d]pyrimidin-7-one |
| Formula | C21H15Cl2FN4O |
| Mass | 429.274 |
| Exact Mass | 428.0606947 |
| Composition | C (58.76%), H (3.52%), Cl (16.52%), F (4.43%), N (13.05%), O (3.73%) |
| Atom Count | 44 |
| PI | 7.49 |
| Smiles | c1c(c(=O)n(C)c2nc(Nc3cc(c(cc3)F)C)ncc12)c1c(cccc1Cl)Cl |
| InChI | 1S/C21H15Cl2FN4O/c1-11-8-13(6-7-17(11)24)26-21-25-10-12-9-14(20(29)28(2)19(12)27-21)18-15(22)4-3-5-1
6(18)23/h3-10H,1-2H3,(H,25,26,27) |
| InChIKey | SLCFEJAMCRLYRG-UHFFFAOYSA-N |
| 2D Structure |  | Structure Backbone |  |
|
| View Structure in Jmol | Click to view 3 d structure Download Mol File |
| Drug Like Property | Druglikeliness |
| Symmetry & Geometry | Symmetry And Geometrical Information |
| Activity & Binding | Activity against isoform and covalant binding information |
| Topological Properties | Descriptors |
| Reference | 10974196 |
| Compounds from Reference | Other compounds from reference |
| Find Similar Compounds | |
| Reported activity against other enzymes | No activity data against other kinases present in database |
| Pub Chem Link |
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| Drug Bank Link | - |
| ChemSpider Link | 4470634 |
| ChEMBL Link | CHEMBL574058 |
