General Property |
Molceule ID (DB) | EGIN0001139 |
Inhibitor Class | Pyrido-pyrimidine |
Molecule Name in Refrence Article | 5 compound |
IUPAC Name | 6-(2,6-dichlorophenyl)-8-methyl-2-(phenylamino)-7H,8H-pyrido[2,3-d]pyrimidin-7-one |
Formula | C20H14Cl2N4O |
Mass | 397.257 |
Exact Mass | 396.0544665 |
Composition | C (60.47%), H (3.55%), Cl (17.85%), N (14.1%), O (4.03%) |
Atom Count | 41 |
PI | 7.41 |
Smiles | c12c(nc(nc1)Nc1ccccc1)n(c(=O)c(c2)c1c(cccc1Cl)Cl)C |
InChI | 1S/C20H14Cl2N4O/c1-26-18-12(11-23-20(25-18)24-13-6-3-2-4-7-13)10-14(19(26)27)17-15(21)8-5-9-16(17)22
/h2-11H,1H3,(H,23,24,25) |
InChIKey | MACKJBHSMLAAGO-UHFFFAOYSA-N |
2D Structure | ![](./image/EGIN0001139.png) | Structure Backbone | ![](./frame/f_EGIN0001139.png) |
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View Structure in Jmol | Click to view 3 d structure Download Mol File |
Drug Like Property | Druglikeliness |
Symmetry & Geometry | Symmetry And Geometrical Information |
Activity & Binding | Activity against isoform and covalant binding information |
Topological Properties | Descriptors |
Reference | 9599227 | 9703473 | |
Compounds from Reference | Other compounds from reference |
Find Similar Compounds | |
Reported activity against other enzymes | FGFr | PDGFr | FGFr | ALL |
Pub Chem Link |
5327885
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Drug Bank Link | - |
ChemSpider Link | 4485055 |
ChEMBL Link | CHEMBL301612 |