Epidermal Growth Factor Receptor Inhibitor Database


General Property
Molceule ID (DB)EGIN0000636
Inhibitor ClassPyrido-pyrimidine
Molecule Name in Refrence ArticleGW9263
IUPAC Name2-[(4-{[4-(benzylamino)-3-carboximidoylphenyl]amino}pyrido[3,4-d]pyrimidin-6-yl)(methyl)amino]ethan-1-ol
FormulaC24H25N7O
Mass427.5016
Exact Mass427.2120585
Composition C (67.43%), H (5.89%), N (22.93%), O (3.74%)
Atom Count57
PI11.89
Smilesc12c(cnc(c1)N(C)CCO)ncnc2Nc1ccc(c(c1)C=N)NCc1ccccc1
InChI1S/C24H25N7O/c1-31(9-10-32)23-12-20-22(15-27-23)28-16-29-24(20)30-19-7-8-21(18(11-19)13-25)26-14-17-
5-3-2-4-6-17/h2-8,11-13,15-16,25-26,32H,9-10,14H2,1H3,(H,28,29,30)/b25-13+
InChIKeyUAHVNJNARPJFOA-DHRITJCHSA-N
2D Structure
Structure Backbone
View Structure in JmolClick to view 3 d structure                            Download Mol File
Drug Like PropertyDruglikeliness
Symmetry & GeometrySymmetry And Geometrical Information
Activity & Binding Activity against isoform and covalant binding information
Topological PropertiesDescriptors
Reference11585755
Compounds from ReferenceOther compounds from reference
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Reported activity against other enzymesNo activity data against other kinases present in database
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