Epidermal Growth Factor Receptor Inhibitor Database


General Property
Molceule ID (DB)EGIN0000608
Inhibitor ClassNaphtho-furo-quinone
Molecule Name in Refrence Article15 compound
IUPAC Namemethyl (2R,11R)-20-[(4-methoxyphenyl)methoxy]-3,10-dioxo-12-oxapentacyclo[11.8.0.0^{2,11}.0^{4,9}.0^{14,19}]henicosa-1(13),4,6,8,14(19),15,17,20-octaene-21-carboxylate
FormulaC30H22O7
Mass494.4915
Exact Mass494.1365531
Composition C (72.87%), H (4.48%), O (22.65%)
Atom Count59
PI0.65
Smilesc12c(cccc1)C(=O)[C@H]1[C@H](C2=O)c2c(O1)c1c(c(c2C(=O)OC)OCc2ccc(cc2)OC)cccc1
InChI1S/C30H22O7/c1-34-17-13-11-16(12-14-17)15-36-27-20-9-5-6-10-21(20)28-22(24(27)30(33)35-2)23-25(31)18
-7-3-4-8-19(18)26(32)29(23)37-28/h3-14,23,29H,15H2,1-2H3/t23-,29+/m0/s1
InChIKeyUCJMTDAVCKJFMT-MUAVYFROSA-N
2D Structure
Structure Backbone
View Structure in JmolClick to view 3 d structure                            Download Mol File
Drug Like PropertyDruglikeliness
Symmetry & GeometrySymmetry And Geometrical Information
Activity & Binding Activity against isoform and covalant binding information
Topological PropertiesDescriptors
Reference16321529
Compounds from ReferenceOther compounds from reference
Find Similar Compounds
                                   

Reported activity against other enzymesFGFR1 | VEGFR2 | PDGFR beta | ALL
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