Epidermal Growth Factor Receptor Inhibitor Database


General Property
Molceule ID (DB)EGIN0000194
Inhibitor ClassDiphenyl-amine
Molecule Name in Refrence Article14f compound
IUPAC NameN'-[(1E)-(2R)-oxolan-2-ylmethylidene]-2-[(4-{N'-[(1E)-(2R)-oxolan-2-ylmethylidene]hydrazinecarbonyl}phenyl)amino]benzohydrazide
FormulaC24H27N5O4
Mass449.5023
Exact Mass449.2063044
Composition C (64.13%), H (6.05%), N (15.58%), O (14.24%)
Atom Count60
PI6.02
Smilesc1c(c(ccc1)C(=O)N/N=C/[C@@H]1OCCC1)Nc1ccc(cc1)C(=O)N/N=C/[C@H]1CCCO1
InChI1S/C24H27N5O4/c30-23(28-25-15-19-5-3-13-32-19)17-9-11-18(12-10-17)27-22-8-2-1-7-21(22)24(31)29-26-16
-20-6-4-14-33-20/h1-2,7-12,15-16,19-20,27H,3-6,13-14H2,(H,28,30)(H,29,31)/b25-15+,26-16+/t19-,20-/m1
/s1
InChIKeyUDELFUBQXDTBSJ-IWTOYXBHSA-N
2D Structure
Structure Backbone
View Structure in JmolClick to view 3 d structure                            Download Mol File
Drug Like PropertyDruglikeliness
Symmetry & GeometrySymmetry And Geometrical Information
Activity & Binding Activity against isoform and covalant binding information
Topological PropertiesDescriptors
Reference20580136
Compounds from ReferenceOther compounds from reference
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Reported activity against other enzymesNo activity data against other kinases present in database
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