Epidermal Growth Factor Receptor Inhibitor Database


Activity against kinases
Molecule Id: EGIN0005100
S.No. Kinase Mutant IC50 Ki Kd Enz. inhib. (%) Inhib. Conc. Cellular IC50 Cell line Growth Factor
1CDK2-10000 nM-------
2ALK-2300 nM-------
3IGF1R-10000 nM-------
4INSR-10000 nM-------
5KIT-540 nM-------
6MET-6400 nM-------
7MST1R-10000 nM-------
8SRC-290 nM-------
9SYK-720 nM-------
10CK1-10000 nM-------
11COT1-10000 nM-------
12CaMK2-10000 nM-------
13ERK2-10000 nM-------
14GSK3β-10000 nM-------
15IRAK4-10000 nM-------
16JAK1-3300 nM-------
17JAK2-1200 nM-------
18JAK3-2600 nM-------
19JNK2-1500 nM-------
20MK2-10000 nM-------
21MK5-10000 nM-------
22MNK1-6700 nM-------
23MNK2-3200 nM-------
24PDK1-10000 nM-------
25PIM2-10000 nM-------
26PKA-1100 nM-------
27PKBa-10000 nM-------
28PKCα-6700 nM-------
29PKCθ-3600 nM-------
30PKN1-6100 nM-------
31PKN2-10000 nM-------
32PLK1-10000 nM-------
33ROCK2-10000 nM-------
34S6K-9400 nM-------
35TYK2-6700 nM-------
36VEGFR2-20 nM-------
37WNK1-10000 nM-------
38p38α-230 nM-------
39p38γ-10000 nM-------