Epidermal Growth Factor Receptor Inhibitor Database


Activity against kinases
Molecule Id: EGIN0004924
S.No. Kinase Mutant IC50 Ki Kd Enz. inhib. (%) Inhib. Conc. Cellular IC50 Cell line Growth Factor
1v-abl kinase->50000 nM-------
2c-src kinase-16000 nM-------
3c-lyn kinase->150000 nM-------
4c-fgr kinase->150000 nM-------
5TPK-IIB kinase->150000 nM-------
6PKA->500000 nM-------
7PPK->500000 nM-------
8CK-1->200000 nM-------
9CK-2->200000 nM-------
10PKC alpha-6000 nM-------
11PKC beta-1-30000 nM-------
12PKC beta-2-4800 nM-------
13PKC gamma-30000 nM-------
14PKC delta->500000 nM-------
15PKC epsilon->500000 nM-------
16PKC zeta->500000 nM-------
17PKC eata->500000 nM-------
18v-abl kinase->50000 nM-------
19c-src kinase-16000 nM-------
20c-lyn kinase->150000 nM-------
21c-fgr kinase->150000 nM-------
22Csk->100000 nM-------
23TPK-IIB kinase->150000 nM-------
24Cyclic AMP-dependent protein kinase->500000 nM-------
25Phosphorylase kinase->500000 nM-------
26Protein kinase CK-1->200000 nM-------
27Protein kinase CK-2->200000 nM-------
28cdc2/cyclin B->10000 nM-------
29PKC alpha-6000 nM-------
30PKC beta-1-30000 nM-------
31PKC beta-2-4800 nM-------
32PKC gamma-30000 nM-------
33PKC delta->500000 nM-------
34PKC epsilon->500000 nM-------
35PK zeta->500000 nM-------
36PKC eata->500000 nM-------