Epidermal Growth Factor Receptor Inhibitor Database
| Activity against kinases |
| Molecule Id: EGIN0004913 |
| S.No. |
Kinase |
Mutant |
IC50 |
Ki |
Kd |
Enz. inhib. (%) |
Inhib. Conc. |
Cellular IC50 |
Cell line |
Growth Factor |
| 1 | Flt-1 | - | >10000 nM | - | - | - | - | - | - | - |
| 2 | KDR | - | >10000 nM | - | - | - | - | - | - | - |
| 3 | PDGFRa | - | >10000 nM | - | - | - | - | - | - | - |
| 4 | PDGFRb | - | >10000 nM | - | - | - | - | - | - | - |
| 5 | c-Src | - | >10000 nM | - | - | - | - | - | - | - |
| 6 | c-Met | - | >10000 nM | - | - | - | - | - | - | - |
| 7 | c-Kit | - | >10000 nM | - | - | - | - | - | - | - |
| 8 | IGF1R | - | >10000 nM | - | - | - | - | - | - | - |
| 9 | FGFR1 | - | >10000 nM | - | - | - | - | - | - | - |
| 10 | RON | - | >10000 nM | - | - | - | - | - | - | - |
| 11 | Abl | - | >10000 nM | - | - | - | - | - | - | - |
| 12 | EphA2 | - | >10000 nM | - | - | - | - | - | - | - |
| 13 | EphB2 | - | >10000 nM | - | - | - | - | - | - | - |
| 14 | Tie2 | - | >10000 nM | - | - | - | - | - | - | - |
| 15 | SYK | - | >10000 nM | - | - | - | - | - | - | - |
| 16 | PKCb2 | - | >10000 nM | - | - | - | - | - | - | - |
| 17 | p70S6K | - | >10000 nM | - | - | - | - | - | - | - |
| 18 | JAK2 | - | >10000 nM | - | - | - | - | - | - | - |
| 19 | Pim2 | - | >10000 nM | - | - | - | - | - | - | - |
| 20 | AKT1 | - | >10000 nM | - | - | - | - | - | - | - |
| 21 | AUR A | - | >10000 nM | - | - | - | - | - | - | - |
| 22 | CDK2 | - | >10000 nM | - | - | - | - | - | - | - |
| 23 | GSK3b | - | >10000 nM | - | - | - | - | - | - | - |
