Epidermal Growth Factor Receptor Inhibitor Database


Activity against kinases
Molecule Id: EGIN0004481
S.No. Kinase Mutant IC50 Ki Kd Enz. inhib. (%) Inhib. Conc. Cellular IC50 Cell line Growth Factor
1LCK-1700 nM-------
2c-met-1800 nM-------
3MEK1-2100 nM-------
4LYNB-3000 nM-------
5TIE2-3200 nM-------
6CSK-3900 nM-------
7LYNA-7100 nM-------
8Src-8400 nM-------
9c-kit->10000 nM-------
10AuroraB ->10000 nM-------
11FGFR1->10000 nM-------
12FGFR3->10000 nM-------
13ASK1->10000 nM-------
14FAK->10000 nM-------
15MEK5->10000 nM-------
16MEKK->10000 nM-------
17VEGFR1->10000 nM-------
18VEGFR2->10000 nM-------
19PDGFRa->10000 nM-------
20PDGFRb->10000 nM-------
21TTK->10000 nM-------
22TAK1->10000 nM-------
23PLK->10000 nM-------
24PKCtheta ->10000 nM-------
25PKA->10000 nM-------
26BMX->10000 nM-------
27IGF1-R->10000 nM-------
28InsR->10000 nM-------
29ZAP70->10000 nM-------
30B-rafw->10000 nM-------
31ERK1->10000 nM-------
32GSK3b->10000 nM-------
33IKK->10000 nM-------
34JNK->10000 nM-------
35P38a->10000 nM-------