Epidermal Growth Factor Receptor Inhibitor Database


Activity against kinases
Molecule Id: EGIN0004282
S.No. Kinase Mutant IC50 Ki Kd Enz. inhib. (%) Inhib. Conc. Cellular IC50 Cell line Growth Factor
1ACK1->10 nM-------
2AKT1->10 nM-------
3ALK->10 nM-------
4AurA-3.565nM-------
5AurB->10 nM-------
6BRK->10 nM-------
7BUB1->10 nM-------
8c-Abl->10 nM-------
9CDC7/DBF4->10 nM-------
10CDK1/CyB-0.006nM-------
11CDK2/CyA-0.002nM-------
12CDK2/CyE-0.008nM-------
13CDK4/CyD1-0.176nM-------
14CDK5/p25-0.006nM-------
15CHK1->10 nM-------
16CK2->10 nM-------
17C-KIT->10 nM-------
18EEF2K->10 nM-------
19ERK2-0.622nM-------
20FAK->10 nM-------
21FGFR1->10 nM-------
22FLT3->10 nM-------
23GSK-3 beta-0.358nM-------
24IGF1R->10 nM-------
25IKK1->10 nM-------
26IKK2->10 nM-------
27IR->10 nM-------
28JAK1->10 nM-------
29JAK3->10 nM-------
30LCK->10 nM-------
31LYN->10 nM-------
32MAPKAPK2->10 nM-------
33MET->10 nM-------
34MNK2->10 nM-------
35MST4->10 nM-------
36NEK6->10 nM-------
37NIM->10 nM-------
38PAK4->10 nM-------
39PDGFR->10 nM-------
40PDK1->10 nM-------
41PERK->10 nM-------
42PIM1->10 nM-------
43PIM2->10 nM-------
44PKAR->10 nM-------
45PKC beta->10 nM-------
46PLK1->10 nM-------
47RET->10 nM-------
48SULU1->10 nM-------
49SYK->10 nM-------
50TRKA->10 nM-------
51TYK->10 nM-------
52VEGFR2->10 nM-------
53VEGFR3->10 nM-------
54ZAP70->10 nM-------