Epidermal Growth Factor Receptor Inhibitor Database


Activity against kinases
Molecule Id: EGIN0004280
S.No. Kinase Mutant IC50 Ki Kd Enz. inhib. (%) Inhib. Conc. Cellular IC50 Cell line Growth Factor
1ACK1->10 nM-------
2AKT1->10 nM-------
3ALK->10 nM-------
4AurA->10 nM-------
5AurB->10 nM-------
6BRK->10 nM-------
7BUB1->10 nM-------
8c-Abl->10 nM-------
9CDC7/DBF4->10 nM-------
10CDK1/CyB-0.005nM-------
11CDK2/CyA-0.002nM-------
12CDK2/CyE-0.007nM-------
13CDK5/p25-0.009nM-------
14CHK1->10 nM-------
15CK2->10 nM-------
16C-KIT->10 nM-------
17EEF2K->10 nM-------
18ERK2-0.212nM-------
19FAK->10 nM-------
20FGFR1->10 nM-------
21FLT3->10 nM-------
22IGF1R->10 nM-------
23IKK1->10 nM-------
24IKK2->10 nM-------
25IR->10 nM-------
26JAK1->10 nM-------
27JAK3->10 nM-------
28LCK->10 nM-------
29LYN->10 nM-------
30MAPKAPK2->10 nM-------
31MET->10 nM-------
32MNK2->10 nM-------
33MST4->10 nM-------
34NEK6->10 nM-------
35NIM->10 nM-------
36PAK4->10 nM-------
37PDGFR->10 nM-------
38PDK1->10 nM-------
39PERK->10 nM-------
40PIM1->10 nM-------
41PIM2->10 nM-------
42PKAR->10 nM-------
43PKC beta->10 nM-------
44PLK1->10 nM-------
45RET->10 nM-------
46SULU1->10 nM-------
47SYK->10 nM-------
48TRKA->10 nM-------
49TYK->10 nM-------
50VEGFR2->10 nM-------
51VEGFR3->10 nM-------
52ZAP70->10 nM-------