Epidermal Growth Factor Receptor Inhibitor Database


Activity against kinases
Molecule Id: EGIN0004275
S.No. Kinase Mutant IC50 Ki Kd Enz. inhib. (%) Inhib. Conc. Cellular IC50 Cell line Growth Factor
1Akt1->10000nM-------
2Aurora B->10000nM-------
3CDK2->10000nM-------
4FGFR1->10000nM-------
5Flt1->10000nM-------
6FLT3->10000nM-------
7IGF1R->10000nM-------
8Kit->10000nM-------
9MAPK1->10000nM-------
10Met->10000nM-------
11PDGFR beta->10000nM-------
12PDGFR alpha->10000nM-------
13PKC alpha->10000nM-------
14Raf1-10000nM-------
15KDR-1300nM-------
16Flt4-2700nM-------
17Lck-300nM-------
18FGFR2-4100nM-------
19Abl1-500nM-------
20Tek-5000nM-------
21Ret-700nM-------
22Src-800nM-------