Epidermal Growth Factor Receptor Inhibitor Database


Activity against kinases
Molecule Id: EGIN0004198
S.No. Kinase Mutant IC50 Ki Kd Enz. inhib. (%) Inhib. Conc. Cellular IC50 Cell line Growth Factor
1AKT1->10000nM-------
2CDC7->10000nM-------
3CHK1->10000nM-------
4CK2->10000nM-------
5ERK2->10000nM-------
6GSK-3 beta->10000nM-------
7IGF1R->10000nM-------
8IKK2->10000nM-------
9IKKi->10000nM-------
10IR->10000nM-------
11LYN->10000nM-------
12MAPKAPK2->10000nM-------
13MET->10000nM-------
14P38a->10000nM-------
15P38ß->10000nM-------
16PAK4->10000nM-------
17PDK1->10000nM-------
18PKA alpha->10000nM-------
19PKC beta->10000nM-------
20PLK1->10000nM-------
21STLK2->10000nM-------
22TRKA->10000nM-------
23VEGFR2->10000nM-------
24Zap70->10000nM-------
25AurA-1051nM-------
26NEK6-1065nM-------
27NIM-1166nM-------
28FGFR1-1207nM-------
29CDK7/H-150nM-------
30CDK4/D1-160nM-------
31RET-1933nM-------
32LCK-209nM-------
33CDK5/p25-265nM-------
34SULU1-2873nM-------
35CDK2/E-363nM-------
36CDK1/B-368nM-------
37AurB-4175nM-------
38CDK2/A-45nM-------
39c-Abl-478nM-------
40TRKA-53nM-------
41PDGFR-579nM-------
42C-KIT-668nM-------
43VEGFR3-920nM-------