Epidermal Growth Factor Receptor Inhibitor Database


Activity against kinases
Molecule Id: EGIN0004172
S.No. Kinase Mutant IC50 Ki Kd Enz. inhib. (%) Inhib. Conc. Cellular IC50 Cell line Growth Factor
1AKT1-6.7 µg/mL-------
2Aurora A-1.3 µg/mL-------
3Aurora B-0.76 µg/mL-------
4CDK4/CycD1-0.64 µg/mL-------
5FAK-1.5 µg/mL-------
6FLT3-4.8 µg/mL-------
7IGF1R-3.5 µg/mL-------
8PLK1-4.8 µg/mL-------
9SAK-2.5 µg/mL-------
10SRC-2.4 µg/mL-------
11TIE2-8.9 µg/mL-------
12VEGFR2-7.3 µg/mL-------
13VEGFR3-9.9 µg/mL-------