Epidermal Growth Factor Receptor Inhibitor Database
| Activity against kinases |
| Molecule Id: EGIN0004156 |
| S.No. |
Kinase |
Mutant |
IC50 |
Ki |
Kd |
Enz. inhib. (%) |
Inhib. Conc. |
Cellular IC50 |
Cell line |
Growth Factor |
| 1 | Akt | - | >10000nM | - | - | - | - | - | - | - |
| 2 | BTK | - | >10000nM | - | - | - | - | - | - | - |
| 3 | CDK4 | - | >10000nM | - | - | - | - | - | - | - |
| 4 | IGFR | - | >10000nM | - | - | - | - | - | - | - |
| 5 | IKK | - | >10000nM | - | - | - | - | - | - | - |
| 6 | KDR | - | >10000nM | - | - | - | - | - | - | - |
| 7 | Lck | - | >10000nM | - | - | - | - | - | - | - |
| 8 | Lyn | - | >10000nM | - | - | - | - | - | - | - |
| 9 | MK2 | - | >10000nM | - | - | - | - | - | - | - |
| 10 | p70 | - | >10000nM | - | - | - | - | - | - | - |
| 11 | PDK1 | - | >10000nM | - | - | - | - | - | - | - |
| 12 | phosphoinositol-3-kinase | - | >10000nM | - | - | - | - | - | - | - |
| 13 | PKA | - | >10000nM | - | - | - | - | - | - | - |
| 14 | Plk | - | >10000nM | - | - | - | - | - | - | - |
| 15 | Raf | - | >10000nM | - | - | - | - | - | - | - |
| 16 | Src | - | >10000nM | - | - | - | - | - | - | - |
| 17 | Tpl2 | - | >10000nM | - | - | - | - | - | - | - |
| 18 | PKC theta | - | 70 ± 30nM | - | - | - | - | - | - | - |
