Epidermal Growth Factor Receptor Inhibitor Database


Activity against kinases
Molecule Id: EGIN0004153
S.No. Kinase Mutant IC50 Ki Kd Enz. inhib. (%) Inhib. Conc. Cellular IC50 Cell line Growth Factor
1Aurora2-116nM-------
2BTK-19nM-------
3CDK5->100000 nM-------
4cFMS-37nM-------
5ERK1->100000 nM-------
6FgfRK->1000 nM-------
7FgfRK2->1000 nM-------
8Flt1->1000 nM-------
9Flt4-120nM-------
10JAK2->25000 nM-------
11JAK3->8300 nM-------
12JNK2->100000 nM-------
13LCK-8nM-------
14MSK1->100000 nM-------
15P38->25000 nM-------
16P70S6-10000nM-------
17PIM1->30000 nM-------
18PIM2->25000 nM-------
19PKA alpha->100000 nM-------
20PKB alpha->100000 nM-------
21Tie2-285nM-------
22ZAP70->5400 nM-------