Epidermal Growth Factor Receptor Inhibitor Database


Activity against kinases
Molecule Id: EGIN0004124
S.No. Kinase Mutant IC50 Ki Kd Enz. inhib. (%) Inhib. Conc. Cellular IC50 Cell line Growth Factor
1ARK5-2.2X10-6 g/mL-------
2Aurora A-1.7X10-6 g/mL-------
3Aurora B-9.8X10-7 g/mL-------
4B-RAF-VE-6.7X10-6 g/mL-------
5CDK4/CycD1-6.4X10-6 g/mL-------
6COT-5.5X10-6 g/mL-------
7EPHB4-8.9X10-6 g/mL-------
8FAK-7.3X10-6 g/mL-------
9FLT3-6.6X10-7 g/mL-------
10IGF1R-1.7X10-6 g/mL-------
11InsR-9.4X10-6 g/mL-------
12MET-7.0X10-6 g/mL-------
13PDGFR beta-7.6X10-6 g/mL-------
14SAK-1.7X10-6 g/mL-------
15SRC-2.1X10-6 g/mL-------
16TIE2-8.8X10-6 g/mL-------
17VEGFR2-1.4X10-6 g/mL-------
18VEGFR3-2.8X10-6 g/mL-------