Epidermal Growth Factor Receptor Inhibitor Database


Activity against kinases
Molecule Id: EGIN0004122
S.No. Kinase Mutant IC50 Ki Kd Enz. inhib. (%) Inhib. Conc. Cellular IC50 Cell line Growth Factor
1ARK5-2.6X10-6 g/mL-------
2Aurora A-2.7X10-6 g/mL-------
3Aurora B-1.5X10-6 g/mL-------
4B-RAF-VE-7.4X10-6 g/mL-------
5CDK4/CycD1-4.4X10-6 g/mL-------
6COT-9.7X10-6 g/mL-------
7EPHB4-5.9X10-6 g/mL-------
8FLT3-1.8X10-6 g/mL-------
9IGF1R-2.4X10-6 g/mL-------
10InsR-3.0X10-6 g/mL-------
11MET-2.5X10-6 g/mL-------
12PDGFR beta-5.8X10-6 g/mL-------
13SAK-1.7X10-6 g/mL-------
14SRC-4.7X10-6 g/mL-------
15TIE2-3.8X10-6 g/mL-------
16VEGFR2-3.8X10-6 g/mL-------
17VEGFR3-6.8X10-6 g/mL-------