Epidermal Growth Factor Receptor Inhibitor Database


Activity against kinases
Molecule Id: EGIN0004120
S.No. Kinase Mutant IC50 Ki Kd Enz. inhib. (%) Inhib. Conc. Cellular IC50 Cell line Growth Factor
1AKT1-5.3X10-6 g/mL-------
2ARK5-3.5X10-7 g/mL-------
3Aurora A-1.5X10-6 g/mL-------
4Aurora B-1.1X10-6 g/mL-------
5B-RAF-VE-1.5X10-6 g/mL-------
6CDK2/CycA-2.4X10-6 g/mL-------
7CDK4/CycD1-1.7X10-6 g/mL-------
8COT-2.3X10-6 g/mL-------
9EPHB4-1.2X10-6 g/mL-------
10FAK-4.9X10-6 g/mL-------
11FLT3-5.3X10-7 g/mL-------
12IGF1R-9.1X10-7 g/mL-------
13InsR-1.3X10-6 g/mL-------
14MET-1.7X10-6 g/mL-------
15PDGFR beta-1.8X10-6 g/mL-------
16PLK1-5.7X10-6 g/mL-------
17SAK-8.3X10-7 g/mL-------
18SRC-1.4X10-6 g/mL-------
19TIE2-1.4X10-6 g/mL-------
20VEGFR2-6.4X10-7 g/mL-------
21VEGFR3-3.9X10-7 g/mL-------