Epidermal Growth Factor Receptor Inhibitor Database


Activity against kinases
Molecule Id: EGIN0004119
S.No. Kinase Mutant IC50 Ki Kd Enz. inhib. (%) Inhib. Conc. Cellular IC50 Cell line Growth Factor
1AKT1-7.9X10-6 g/mL-------
2ARK5-4.0X10-6 g/mL-------
3Aurora A-5.0X10-6 g/mL-------
4Aurora B-1.3X10-6 g/mL-------
5B-RAF-VE-4.8X10-6 g/mL-------
6CDK2/CycA-3.6X10-6 g/mL-------
7CDK4/CycD1-2.1X10-6 g/mL-------
8COT-2.6X10-6 g/mL-------
9EPHB4-1.4X10-6 g/mL-------
10FAK-8.9X10-6 g/mL-------
11FLT3-1.0X10-6 g/mL-------
12IGF1R-1.7X10-6 g/mL-------
13InsR-7.9X10-6 g/mL-------
14PDGFR beta-1.8X10-6 g/mL-------
15PLK1-8.2X10-6 g/mL-------
16SAK-2.5X10-6 g/mL-------
17SRC-1.2X10-6 g/mL-------
18TIE2-3.5X10-6 g/mL-------
19VEGFR2-1.1X10-6 g/mL-------
20VEGFR3-9.6X10-7 g/mL-------