Epidermal Growth Factor Receptor Inhibitor Database


Activity against kinases
Molecule Id: EGIN0004115
S.No. Kinase Mutant IC50 Ki Kd Enz. inhib. (%) Inhib. Conc. Cellular IC50 Cell line Growth Factor
1BTK->10000nM-------
2EGFR->10000nM-------
3GSK-3->10000nM-------
4IGFR->10000nM-------
5IKK beta->10000nM-------
6KDR->10000nM-------
7MEK1->10000nM-------
8MK2->200000nM-------
9PDK1->200000nM-------
10AKT1->30000nM-------
11LCK->30000nM-------
12LYN->30000nM-------
13S6K1->30000nM-------
14Tpl2->40000nM-------
15CDK4->50000nM-------
16PI3K delta-11nM-------
17PI3K beta-13nM-------
18mTOR-2920nM-------
19PI3K alpha-6.4nM-------
20PI3K gamma-8nM-------