Epidermal Growth Factor Receptor Inhibitor Database
Activity against kinases |
Molecule Id: EGIN0004115 |
S.No. |
Kinase |
Mutant |
IC50 |
Ki |
Kd |
Enz. inhib. (%) |
Inhib. Conc. |
Cellular IC50 |
Cell line |
Growth Factor |
1 | BTK | - | >10000nM | - | - | - | - | - | - | - |
2 | EGFR | - | >10000nM | - | - | - | - | - | - | - |
3 | GSK-3 | - | >10000nM | - | - | - | - | - | - | - |
4 | IGFR | - | >10000nM | - | - | - | - | - | - | - |
5 | IKK beta | - | >10000nM | - | - | - | - | - | - | - |
6 | KDR | - | >10000nM | - | - | - | - | - | - | - |
7 | MEK1 | - | >10000nM | - | - | - | - | - | - | - |
8 | MK2 | - | >200000nM | - | - | - | - | - | - | - |
9 | PDK1 | - | >200000nM | - | - | - | - | - | - | - |
10 | AKT1 | - | >30000nM | - | - | - | - | - | - | - |
11 | LCK | - | >30000nM | - | - | - | - | - | - | - |
12 | LYN | - | >30000nM | - | - | - | - | - | - | - |
13 | S6K1 | - | >30000nM | - | - | - | - | - | - | - |
14 | Tpl2 | - | >40000nM | - | - | - | - | - | - | - |
15 | CDK4 | - | >50000nM | - | - | - | - | - | - | - |
16 | PI3K delta | - | 11nM | - | - | - | - | - | - | - |
17 | PI3K beta | - | 13nM | - | - | - | - | - | - | - |
18 | mTOR | - | 2920nM | - | - | - | - | - | - | - |
19 | PI3K alpha | - | 6.4nM | - | - | - | - | - | - | - |
20 | PI3K gamma | - | 8nM | - | - | - | - | - | - | - |