Epidermal Growth Factor Receptor Inhibitor Database
| Activity against kinases |
| Molecule Id: EGIN0004026 |
| S.No. |
Kinase |
Mutant |
IC50 |
Ki |
Kd |
Enz. inhib. (%) |
Inhib. Conc. |
Cellular IC50 |
Cell line |
Growth Factor |
| 1 | calmodulin kinase | - | >100000nM | - | - | - | - | - | - | - |
| 2 | casein kinase 2 | - | >100000nM | - | - | - | - | - | - | - |
| 3 | insulin kinase beta | - | >100000nM | - | - | - | - | - | - | - |
| 4 | PKA | - | >100000nM | - | - | - | - | - | - | - |
| 5 | PKC beta2 | - | >100000nM | - | - | - | - | - | - | - |
| 6 | CDK4/cyclinD1 | - | 110nM | - | - | - | - | - | - | - |
| 7 | Casein Kinase 1 | - | 11200nM | - | - | - | - | - | - | - |
| 8 | PDGFR beta | - | 11800nM | - | - | - | - | - | - | - |
| 9 | VEGFR2 | - | 130nM | - | - | - | - | - | - | - |
| 10 | MAP kinase/ERK2 | - | 19400nM | - | - | - | - | - | - | - |
| 11 | CDK2/cyclinA | - | 2nM | - | - | - | - | - | - | - |
| 12 | FGFR2 | - | 220nM | - | - | - | - | - | - | - |
| 13 | PKC alpha/gamma | - | 30100nM | - | - | - | - | - | - | - |
| 14 | GSK-3 | - | 41nM | - | - | - | - | - | - | - |
| 15 | CDK1/cyclinB | - | 6nM | - | - | - | - | - | - | - |
