Epidermal Growth Factor Receptor Inhibitor Database
| Activity against kinases |
| Molecule Id: EGIN0004024 |
| S.No. |
Kinase |
Mutant |
IC50 |
Ki |
Kd |
Enz. inhib. (%) |
Inhib. Conc. |
Cellular IC50 |
Cell line |
Growth Factor |
| 1 | Abl | - | >30000nM | - | - | - | - | - | - | - |
| 2 | CSF1R | - | >30000nM | - | - | - | - | - | - | - |
| 3 | Erk | - | >30000nM | - | - | - | - | - | - | - |
| 4 | Jnk | - | >30000nM | - | - | - | - | - | - | - |
| 5 | Mek1 | - | >30000nM | - | - | - | - | - | - | - |
| 6 | Mkk6 | - | >30000nM | - | - | - | - | - | - | - |
| 7 | p38 | - | >30000nM | - | - | - | - | - | - | - |
| 8 | PKA | - | >30000nM | - | - | - | - | - | - | - |
| 9 | PKC | - | >30000nM | - | - | - | - | - | - | - |
| 10 | Src | - | >30000nM | - | - | - | - | - | - | - |
| 11 | beta PDGFR | - | 140nM | - | - | - | - | - | - | - |
| 12 | Flt3 | - | 14900nM | - | - | - | - | - | - | - |
| 13 | FGFR | - | 160000nM | - | - | - | - | - | - | - |
| 14 | VEGFR2 | - | 17300nM | - | - | - | - | - | - | - |
| 15 | alpha-PDGFR | - | 210nM | - | - | - | - | - | - | - |
| 16 | c-kit | - | 220nM | - | - | - | - | - | - | - |
