Epidermal Growth Factor Receptor Inhibitor Database


Activity against kinases
Molecule Id: EGIN0004023
S.No. Kinase Mutant IC50 Ki Kd Enz. inhib. (%) Inhib. Conc. Cellular IC50 Cell line Growth Factor
1VEGFR2->100000nM-------
2FGFR->200000nM-------
3CSF1R->30000nM-------
4Erk->30000nM-------
5Flt3->30000nM-------
6Jnk->30000nM-------
7Mek1->30000nM-------
8Mkk3->30000nM-------
9Mkk6->30000nM-------
10p38->30000nM-------
11PKA->30000nM-------
12PKC->30000nM-------
13Src->30000nM-------
14alpha-PDGFR-240nM-------
15c-kit-360nM-------
16beta PDGFR-550nM-------