Epidermal Growth Factor Receptor Inhibitor Database


Activity against kinases
Molecule Id: EGIN0003979
S.No. Kinase Mutant IC50 Ki Kd Enz. inhib. (%) Inhib. Conc. Cellular IC50 Cell line Growth Factor
1VEGFR2->100000nM-------
2FGFR->200000nM-------
3CSF1R->30000nM-------
4ERK2->30000nM-------
5Jnk1->30000nM-------
6Mek1->30000nM-------
7Mkk3->30000nM-------
8Mkk6->30000nM-------
9p38->30000nM-------
10PKA->30000nM-------
11PKC->30000nM-------
12Src->30000nM-------
13Flt3-19700nM-------
14PDGFR beta-450nM-------
15c-Kit-480nM-------
16PDGFR alpha-770nM-------