Epidermal Growth Factor Receptor Inhibitor Database
Activity against kinases |
Molecule Id: EGIN0003979 |
S.No. |
Kinase |
Mutant |
IC50 |
Ki |
Kd |
Enz. inhib. (%) |
Inhib. Conc. |
Cellular IC50 |
Cell line |
Growth Factor |
1 | VEGFR2 | - | >100000nM | - | - | - | - | - | - | - |
2 | FGFR | - | >200000nM | - | - | - | - | - | - | - |
3 | CSF1R | - | >30000nM | - | - | - | - | - | - | - |
4 | ERK2 | - | >30000nM | - | - | - | - | - | - | - |
5 | Jnk1 | - | >30000nM | - | - | - | - | - | - | - |
6 | Mek1 | - | >30000nM | - | - | - | - | - | - | - |
7 | Mkk3 | - | >30000nM | - | - | - | - | - | - | - |
8 | Mkk6 | - | >30000nM | - | - | - | - | - | - | - |
9 | p38 | - | >30000nM | - | - | - | - | - | - | - |
10 | PKA | - | >30000nM | - | - | - | - | - | - | - |
11 | PKC | - | >30000nM | - | - | - | - | - | - | - |
12 | Src | - | >30000nM | - | - | - | - | - | - | - |
13 | Flt3 | - | 19700nM | - | - | - | - | - | - | - |
14 | PDGFR beta | - | 450nM | - | - | - | - | - | - | - |
15 | c-Kit | - | 480nM | - | - | - | - | - | - | - |
16 | PDGFR alpha | - | 770nM | - | - | - | - | - | - | - |