Epidermal Growth Factor Receptor Inhibitor Database
| Activity against kinases |
| Molecule Id: EGIN0003975 |
| S.No. |
Kinase |
Mutant |
IC50 |
Ki |
Kd |
Enz. inhib. (%) |
Inhib. Conc. |
Cellular IC50 |
Cell line |
Growth Factor |
| 1 | VEGFR2 | - | >100000nM | - | - | - | - | - | - | - |
| 2 | FGFR | - | >200000nM | - | - | - | - | - | - | - |
| 3 | CSF1R | - | >30000nM | - | - | - | - | - | - | - |
| 4 | ERK2 | - | >30000nM | - | - | - | - | - | - | - |
| 5 | Jnk1 | - | >30000nM | - | - | - | - | - | - | - |
| 6 | Mek1 | - | >30000nM | - | - | - | - | - | - | - |
| 7 | Mkk3 | - | >30000nM | - | - | - | - | - | - | - |
| 8 | Mkk6 | - | >30000nM | - | - | - | - | - | - | - |
| 9 | p38 | - | >30000nM | - | - | - | - | - | - | - |
| 10 | PKA | - | >30000nM | - | - | - | - | - | - | - |
| 11 | PKC | - | >30000nM | - | - | - | - | - | - | - |
| 12 | Src | - | >30000nM | - | - | - | - | - | - | - |
| 13 | beta PDGFR | - | 240nM | - | - | - | - | - | - | - |
| 14 | Flt3 | - | 3300nM | - | - | - | - | - | - | - |
| 15 | c-Kit | - | 390nM | - | - | - | - | - | - | - |
| 16 | alpah-PDGFR | - | 890nM | - | - | - | - | - | - | - |
