Epidermal Growth Factor Receptor Inhibitor Database
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| Activity against kinases | ||||||||||||||
| Molecule Id: EGIN0003972 | ||||||||||||||
| S.No. | Kinase | Mutant | IC50 | Ki | Kd | Enz. inhib. (%) | Inhib. Conc. | Cellular IC50 | Cell line | Growth Factor | ||||
| 1 | GSK-3 | - | 1750nM | - | - | - | - | - | - | - | ||||
| 2 | CDK4/D1 | - | 1920nM | - | - | - | - | - | - | - | ||||
| 3 | CDK2/A | - | 2980nM | - | - | - | - | - | - | - | ||||
| 4 | CDK1/B | - | 800nM | - | - | - | - | - | - | - | ||||
| 5 | PKCR | - | - | - | - | 21 | 10 µM | - | - | - | ||||
| 6 | VEGF-KDR | - | - | - | - | 25 | 10 µM | - | - | - | ||||