Epidermal Growth Factor Receptor Inhibitor Database
| Activity against kinases |
| Molecule Id: EGIN0003509 |
| S.No. |
Kinase |
Mutant |
IC50 |
Ki |
Kd |
Enz. inhib. (%) |
Inhib. Conc. |
Cellular IC50 |
Cell line |
Growth Factor |
| 1 | Cdk2 | - | >30000nM | - | - | - | - | - | - | - |
| 2 | CHK1 | - | >30000nM | - | - | - | - | - | - | - |
| 3 | Csk | - | >30000nM | - | - | - | - | - | - | - |
| 4 | EGFR | - | >30000nM | - | - | - | - | - | - | - |
| 5 | IGFR1 | - | >30000nM | - | - | - | - | - | - | - |
| 6 | Jnk1 | - | >30000nM | - | - | - | - | - | - | - |
| 7 | Kdr | - | >30000nM | - | - | - | - | - | - | - |
| 8 | Pak1 | - | >30000nM | - | - | - | - | - | - | - |
| 9 | PKA | - | >30000nM | - | - | - | - | - | - | - |
| 10 | Plk | - | >30000nM | - | - | - | - | - | - | - |
| 11 | Src | - | >30000nM | - | - | - | - | - | - | - |
| 12 | FGFR1 | - | 13000nM | - | - | - | - | - | - | - |
| 13 | Jak2 | - | 29000nM | - | - | - | - | - | - | - |
| 14 | PDGFR beta | - | 31nM | - | - | - | - | - | - | - |
| 15 | PTK2 | - | 478nM | - | - | - | - | - | - | - |
| 16 | CSF1R | - | 5nM | - | - | - | - | - | - | - |
| 17 | p38 alpha | - | 5nM | - | - | - | - | - | - | - |
| 18 | EphB4 | - | 672nM | - | - | - | - | - | - | - |
