Epidermal Growth Factor Receptor Inhibitor Database
| Activity against kinases |
| Molecule Id: EGIN0003398 |
| S.No. |
Kinase |
Mutant |
IC50 |
Ki |
Kd |
Enz. inhib. (%) |
Inhib. Conc. |
Cellular IC50 |
Cell line |
Growth Factor |
| 1 | calmodulin kinase-2 | - | >10000nM | - | - | - | - | - | - | - |
| 2 | Casein kinase 1 | - | >10000nM | - | - | - | - | - | - | - |
| 3 | Casein kinase 2 | - | >10000nM | - | - | - | - | - | - | - |
| 4 | CDK1 | - | >10000nM | - | - | - | - | - | - | - |
| 5 | CDK4 | - | >10000nM | - | - | - | - | - | - | - |
| 6 | MAPK/ERK2 | - | >10000nM | - | - | - | - | - | - | - |
| 7 | PKA | - | >10000nM | - | - | - | - | - | - | - |
| 8 | PKC beta2 | - | >10000nM | - | - | - | - | - | - | - |
| 9 | PKC gamma | - | >10000nM | - | - | - | - | - | - | - |
| 10 | Insulin R kinase | - | 1690nM | - | - | - | - | - | - | - |
| 11 | FGFR-2 | - | 210nM | - | - | - | - | - | - | - |
| 12 | PDGFR | - | 360nM | - | - | - | - | - | - | - |
| 13 | GSK-3 | - | 478nM | - | - | - | - | - | - | - |
| 14 | VEGFR2 | - | 84nM | - | - | - | - | - | - | - |
