Epidermal Growth Factor Receptor Inhibitor Database
| Activity against kinases |
| Molecule Id: EGIN0003288 |
| S.No. |
Kinase |
Mutant |
IC50 |
Ki |
Kd |
Enz. inhib. (%) |
Inhib. Conc. |
Cellular IC50 |
Cell line |
Growth Factor |
| 1 | Itk | - | >10000nM | - | - | - | - | - | - | - |
| 2 | HGFR | - | >100000nM | - | - | - | - | - | - | - |
| 3 | IGFR | - | >100000nM | - | - | - | - | - | - | - |
| 4 | insulinRK | - | >100000nM | - | - | - | - | - | - | - |
| 5 | PKA | - | >100000nM | - | - | - | - | - | - | - |
| 6 | VEGFR | - | >100000nM | - | - | - | - | - | - | - |
| 7 | Erk | - | >30000nM | - | - | - | - | - | - | - |
| 8 | PKC | - | >300000nM | - | - | - | - | - | - | - |
| 9 | syk | - | >40000nM | - | - | - | - | - | - | - |
| 10 | src | - | 0.2nM | - | - | - | - | - | - | - |
| 11 | Btk | - | 0.4nM | - | - | - | - | - | - | - |
| 12 | lck | - | 0.5nM | - | - | - | - | - | - | - |
| 13 | p38 | - | 150nM | - | - | - | - | - | - | - |
| 14 | lyn | - | 2nM | - | - | - | - | - | - | - |
| 15 | zap70 | - | 400nM | - | - | - | - | - | - | - |
| 16 | IKKR BETA | - | 50000nM | - | - | - | - | - | - | - |
| 17 | IKKR ALPHA | - | 50000nM | - | - | - | - | - | - | - |
| 18 | PDGFR | - | 8nM | - | - | - | - | - | - | - |
