Epidermal Growth Factor Receptor Inhibitor Database
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| Activity against kinases | ||||||||||||||
| Molecule Id: EGIN0003269 | ||||||||||||||
| S.No. | Kinase | Mutant | IC50 | Ki | Kd | Enz. inhib. (%) | Inhib. Conc. | Cellular IC50 | Cell line | Growth Factor | ||||
| 1 | CDK1/cyclinB | - | 297nM | - | - | - | - | - | - | - | ||||
| 2 | CDK2/cyclinE | - | 21nM | - | - | - | - | - | - | - | ||||
| 3 | CDK4/cyclinD1 | - | 2250nM | - | - | - | - | - | - | - | ||||
| 4 | EMT | - | >10000 nM | - | - | - | - | - | - | - | ||||
| 5 | Her2 | - | >25000 nM | - | - | - | - | - | - | - | ||||
| 6 | IGFR | - | >25000 nM | - | - | - | - | - | - | - | ||||
| 7 | PKC alpha | - | >45 nM | - | - | - | - | - | - | - | ||||