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Activity against kinases | ||||||||||||||
Molecule Id: EGIN0003118 | ||||||||||||||
S.No. | Kinase | Mutant | IC50 | Ki | Kd | Enz. inhib. (%) | Inhib. Conc. | Cellular IC50 | Cell line | Growth Factor | ||||
1 | CDK5/p25 | - | - | - | - | 59.83±0.55 | 10 µM | - | - | - | ||||
2 | CK1a1 | - | - | - | - | 100.18±3.12 | 10 µM | - | - | - | ||||
3 | CK2a | - | - | - | - | 77.02±1.08 | 10 µM | - | - | - | ||||
4 | EGFR | - | - | - | - | 32.67±0.68 | 10 µM | - | - | - | ||||
5 | ERK1 | - | - | - | - | 109.58±1.32 | 10 µM | - | - | - | ||||
6 | GSK-3b | - | - | - | - | 18.57±0.07 | 10 µM | - | - | - | ||||
7 | IGF1R | - | - | - | - | 96.24±3.88 | 10 µM | - | - | - | ||||
8 | JNK1 | - | - | - | - | 93.28±0.79 | 10 µM | - | - | - | ||||
9 | MAPKAPK2 | - | - | - | - | 78.23±0.90 | 10 µM | - | - | - | ||||
10 | TYRO3/SKY | - | - | - | - | 96.72±1.43 | 10 µM | - | - | - |