Epidermal Growth Factor Receptor Inhibitor Database


Activity against kinases
Molecule Id: EGIN0002550
S.No. Kinase Mutant IC50 Ki Kd Enz. inhib. (%) Inhib. Conc. Cellular IC50 Cell line Growth Factor
1BRAFV600E264nM-------
2C-Raf-107.1nM-------
3FGFR3----0.110µM---
4IGF-1R----0.710µM---
5mTOR/FRAP1----1.210µM---
6GSK3-beta----1.410µM---
7FAK/PTK2----1.510µM---
8AKT1----3.710µM---
9PLK1----6.310µM---
10TRKB/NTRK2----6.610µM---
11JNK1a1----7.110µM---
12ALK----7.710µM---
13c-MET----1310µM---
14FLT3----1310µM---
15JNK3/MAPK10----1310µM---
16c-Src----1610µM---
17EGFR/ERBB1----1610µM---
18b-RAFV599E---9710µM---
19RAF1----10010µM---