Epidermal Growth Factor Receptor Inhibitor Database
Activity against kinases |
Molecule Id: EGIN0000627 |
S.No. |
Kinase |
Mutant |
IC50 |
Ki |
Kd |
Enz. inhib. (%) |
Inhib. Conc. |
Cellular IC50 |
Cell line |
Growth Factor |
1 | PKA | - | - | - | - | 50 | 10µg/mL | - | - | - |
2 | PKA | - | - | - | - | 50 | 1µg/mL | - | - | - |
3 | PKA | - | - | - | - | 50 | 0.1µg/mL | - | - | - |
4 | PKC | - | - | - | - | 50 | 10µg/mL | - | - | - |
5 | PKC | - | - | - | - | 50 | 1µg/mL | - | - | - |
6 | PKC | - | - | - | - | 50 | 0.1µg/mL | - | - | - |
7 | v-Src | - | - | - | - | 50 | 10µg/mL | - | - | - |
8 | v-Src | - | - | - | - | 50 | 1µg/mL | - | - | - |
9 | v-Src | - | - | - | - | 50 | 0.1µg/mL | - | - | - |
10 | eEF2K | - | - | - | - | 50 | 10µg/mL | - | - | - |
11 | eEF2K | - | - | - | - | 50 | 1µg/mL | - | - | - |
12 | eEF2K | - | - | - | - | 50 | 0.1µg/mL | - | - | - |
13 | Flt-1 | - | - | - | - | 50 | 10µg/mL | - | - | - |
14 | Flt-1 | - | - | - | - | 50 | 1µg/mL | - | - | - |
15 | Flt-1 | - | - | - | - | 50 | 0.1µg/mL | - | - | - |