Epidermal Growth Factor Receptor Inhibitor Database
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| Activity against kinases | ||||||||||||||
| Molecule Id: EGIN0000410 | ||||||||||||||
| S.No. | Kinase | Mutant | IC50 | Ki | Kd | Enz. inhib. (%) | Inhib. Conc. | Cellular IC50 | Cell line | Growth Factor | ||||
| 1 | ABL-1 | - | - | - | - | 1 | 50µM | - | - | - | ||||
| 2 | VEGFR-1 or FLT1 | - | - | - | - | 7.3 | 50µM | - | - | - | ||||
| 3 | VEGFR-2 or KDR | - | - | - | - | 33.1 | 50µM | - | - | - | ||||
| 4 | PDGFR alpha | - | - | - | - | 42.7 | 50µM | - | - | - | ||||
| 5 | PDGFR beta | - | - | - | - | 52.6 | 50µM | - | - | - | ||||